SAM-e

SAM-e (S-Adenosyl-L-Methionine) by Xymogen is a universal methyl donor supporting over 100 methylation reactions throughout the body. Promotes joint comfort, liver health, and neurological function, including healthy mood through neurotransmitter methylation support.

$77.00

Primary methyl donor for over 100 methylation reactions throughout the body
Supports healthy mood through methylation of serotonin, dopamine, and norepinephrine
Promotes joint cartilage synthesis and healthy inflammatory response
Supports Phase II liver methylation detoxification pathway

Why Catalyst Recommends This

SAM-e is the universal methyl donor required for neurotransmitter synthesis, DNA methylation, and detoxification, making it relevant for individuals with methylation insufficiency, mood fluctuations, or everyday cognitive and physical demands.

Suggested Use

Take on an empty stomach as directed. SAM-e is best absorbed without food. Start at lower doses and titrate up, it can be energizing and may worsen occasional stress in sensitive individuals.

Product Disclaimers

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Keep out of reach of children. Do not use if the safety seal is broken or missing. Store in a cool, dry place out of direct sunlight.

Consult with your healthcare practitioner before using this product, especially if you are pregnant, nursing, under 18 years of age, taking medications, or managing a medical condition.

This formula provides S-Adenosyl-L-Methionine (SAM-e), a naturally occurring compound synthesized from methionine and ATP, as the primary methyl group donor in transmethylation reactions including catecholamine methylation (COMT enzyme pathway for dopamine and epinephrine), neurotransmitter synthesis support, DNA/histone methylation for gene regulation, phospholipid methylation for neuronal membrane fluidity, and glutathione synthesis through the transsulfuration pathway.*

Other ingredients: HPMC (capsule), microcrystalline cellulose, ascorbyl palmitate, calcium oxide, silica, and calcium chloride anhydrous.